Biomechanical Modeling and Failure Analysis in Total Knee Replacement: Development and Implementation of the Isotropic Crushable Foam Model

This dissertation investigates the application of the isotropic crushable foam (ICF) model to enhance the prediction of bone behavior around total knee arthroplasty (TKA). The ICF model was characterized using mechanical properties of trabecular bone, demonstrating accurate simulation of bone failure. It was extended to whole bones, improving fracture prediction over conventional models. The model effectively captured the influence of bone properties on initial TKA implant stability, accurately replicating micromotions and plastic deformations. Finally, long-term simulations showed the ICF model's capability to assess implant failure risk due to postoperative bone loss, underscoring its clinical relevance in orthopedic biomechanics.