Unraveling chronic fatigue in childhood cancer survivors

With this study we aimed to address currently existing knowledge gaps by investigating factors that are associated with chronic fatigue (CF) and to determine the consequences of CF. We showed that CF is a symptom that deserves attention and that it needs to be recognized as a debilitating symptom that frequently occurs in survivors of childhood cancer and therefore should be screened for regularly. Together with the survivor, factors that might be related to the CF and could play a role in maintaining the symptoms should be discussed, with a focus on lifestyle and psychosocial factors. Future studies should investigate which interventions are effective to reduce fatigue in CCS and how interventions can be personalized to specific CF subgroups.